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The normal intestinal microbiota triggers the epithelium for synthesizing mucus sugars, while selected commensal bacteria such as Akkermansia muciniphila regulate mucus layers by utilizing mucins as an energy source [67],[68]

This review focuses on the biosynthesis of EGT via microbial fermentation, explores its biosynthetic mechanisms, and summarizes the latest advancements for industrial EGT production using engineered microbial strains

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