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SKU: 11777215824
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SKU: 11777215824 · From iglepidom.org

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On the other hand, traditional pharmacokinetics evaluation of covalent drug metabolism using hepatocytes or microsomes can potentially overlook the contribution from the non-oxidative metabolism pathway through extrahepatic GSH or albumin conjugation, accounting for up to 30% of total conversion in the case of ibrutinib [117]