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However, unlike optimized clinical LRRK2 inhibitors, esculetins pharmacokinetics, brain exposure, and safety in humans with PD remain unknown, so its role is currently limited to proof-of-concept rather than a validated therapeutic
Folate receptors Folate receptors (FR) are overexpressed, or it is seen that FRs overexpress in ovarian, breast, and colorectal cancer
Front Neurosci 13: