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48 Parkinsons disease Aside from the aggregation of misfolded -synuclein in the intracellular Lewy bodies, a major neuropathological hallmark of PD is the loss of dopaminergic neurons within the SN

10.1002/2211-5463.12635 37 HadiA.PourmasoumiM.KafeshaniM.KarimianJ.MaracyM

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a diagnostic procedure used to assess microvascular function and endothelial health to evaluate blood flow changes in response to temporary occlusion of an artery), combined with microcirculatory parameters (e.g., blood flow response), achieved 84.6% accuracy in diagnosing DPN