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980,981 A Phase 3, multicenter, randomized trial (EudraCT 2012-000353-31, NCT01825512) compared the efficacy of DFX and DFP in pediatric patients with transfusion-dependent haemoglobinopathies and found that DFP was more effective and safer in controlling iron overload than DFX over a 12-month treatment period

2 Estimates suggest that as many as 65% of older adults in the United States are exposed to polypharmacy and 29% to PIMs

The authors identified only three published human pilot studies, all small and methodologically limited