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According to the EFSAs vitamin B12 review, Haematological effects of vitamin B12 deficiency include amongst others a gradual onset of the common symptoms of anaemia, such as diminished energy and exercise tolerance, fatigue, shortness of breath and palpitations

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Gastric emptying may be delayed, requiring caution for procedures involving sedation or general anesthesia due to aspiration risk Use caution in those with a history of diabetic retinopathy 5 Avoid use during pregnancy and breastfeeding 6 Enhances glucose-dependent insulin secretion Suppresses glucagon secretion Supports weight loss Slows gastric emptying Improves insulin sensitivity 1,2 Influences brain regions involved in appetite regulation, leading to reduced hunger and caloric intake Helps to decrease internal inflammation 1 Q: How long does it take to see results

Critically, longer-term use was not associated with any increased risk of cardiovascular events or death