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For example, when genotoxic stress-induced DNA damage, TRAF2 and its partner TRAF-interacting protein with forkhead-associated domain (TIFA) enhance ubiquitination of NF-B essential modulator (NEMO) to activate the NF-B pathway [174]

I., & Fornaciari, G

The findings show that the creation of HBs with residues in the active site was the main mechanism stabilizing the compound-protein complexes, which were further supported by other stabilizing factors, such as pi-sigma, alkyl/pi-alkyl, and pi-pi stacking interactions 57,84