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PMID: 40401576 Mol Cancer Ther Unfolded Protein Response as a Therapeutic Target: 4-(Heptyloxy)phenol Induces Programmed Cell Death in Ewing Sarcoma

5 GLN metabolism in leukemia Leukemia is a myeloid malignancy characterized by abnormal proliferation and differentiation of hematopoietic precursor cells

Setosphaeria turcica ATR turns off appressorium-mediated maize infection and triggers melanin-involved self-protection in response to genotoxic stress

Beyond their metabolic roles, they help shape epigenetic states by supplying chromatin-modifying metabolites, directly modifying chromatin structures via post-translational modifications, and acting as scaffold proteins in epigenetic complexes 13,14