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Q., Li, S

Moreover, expression of glutamate-cysteine ligase (GCL) and GSH synthetase was increased dramatically by QUR, in astrocytes and attenuated inflammation by repression of IL-1,6,8, monocyte chemoattractant protein-1 and ROS production release (Chen et al., 2006

Indeed, studies of tumors with poor immunogenicity (e.g., pancreas or prostate) have demonstrated that insufficient tumor antigens prime suboptimal or poor antitumor immunity, likely rendering ineffective anti-PD therapy