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in vivo studies (animal models): It's absolutely paramount to consult existing scientific literature, particularly peer-reviewed articles, specific to your chosen model and research question

Critical Functions of B12 in the Body Vitamin B12 helps make red blood cells, supports the nervous system, and is needed for DNA

Adipocyte Biology and Body Mass Models In rodent models, NNMT expression in adipose tissue has been linked to adipocyte size, lipid accumulation, and changes in energy expenditure