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Brown at RevitalIV

Enhancing NAD(+) salvage metabolism is neuroprotective in a PINK1 model of Parkinsons disease

It is studied in adults with overweight or obesity (BMI 27 or higher in REDEFINE 1) and in adults with type 2 diabetes (REDEFINE 2 and REIMAGINE 2)

It is not appropriate for everyone, and understanding who benefits most helps researchers make informed decisions about whether the added complexity and cost are justified