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According to Mishra et al., the immunomodulatory actions of the drug may be responsible for its antibacterial activity by boosting the bodys inbuilt defenses against microbial infections [9]

YZH and YH designed and carried out all the experiments

We hypothesize that stimulating key regenerative pathways in transplanted hepatocytes using hepatocyte growth factor (HGF) and epidermal growth factor (EGF) and preconditioning the host liver with P21 expression to prevent host hepatocyte proliferation will improve survival, proliferation, and engraftment of PHHs and HLCs in an injured mouse liver

Notably, IL-6 not only modulates hepcidin to affect the release of stored iron from ATMs and intestinal absorption, but also reduces transferrin expression and aggravates iron accumulation by promoting hepcidin production