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doi: 10.1016/j.bcp.2014.01.008 207 MossD

2016, 2016, pp

Toxicants usually appear in only small numbers of cells of the brain, so one cannot use bulk chemistry to detect them due to the dilution effect of the non-toxicant containing cells

Inhibiting glycolysis through hexokinase knockdown in preclinical models acutely attenuated microglial activation and proinflammatory cytokine release after ischemic injury [65]