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doi: 10.1016/j.jaci.2003.07.003 42 AdkinsB

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Blair BG, Larson CA, Safaei R, Howell SB (2009) Copper transporter 2 regulates the cellular accumulation and cytotoxicity of cisplatin and carboplatin

Thus, there is an apparent contradiction: on the one hand there is ample evidence for a role of ROS in various diseases, and antioxidant-rich food is generally associated with health, but antioxidant supplements do not prevent disease and are even associated with a poor health outcome