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Focal transient CNS vessel leak provides a tissue niche for sequential immune cell accumulation during the asymptomatic phase of EAE induction

A microphysiological cell-culturing system for pharmacokinetic drug exposure and high-resolution imaging of arrays of 3D microtissues

0.22 m) immediately prior to use Aliquot and store reconstituted solutions at 20 C (or lower) to minimise degradation Avoid repeated freezethaw cycles Specifications Summary Precautions & Notes Experimental behaviour of IGF-1 LR3 is influenced by receptor expression, concentration, and exposure duration Modified IGF-1 analogues may exhibit signalling profiles distinct from native IGF-1 Buffer composition, pH, and ionic strength may affect peptide stability and assay performance Appropriate controls are recommended to distinguish specific from non-specific effects Intended strictly for laboratory research use

Aug 2008;138(8):1578S-1583S