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Description

thermodynamic or electrochemical parameters in GSH-dependent redox events

Statistical analysis was done using Prism 7.0 (Graphpad software)

TIGAR inhibits excessive autophagy and the degradation of tight junction proteins by promoting the flux of pentose phosphate pathway (PPP) and the production of nicotinamide adenine dinucleotide phosphate (NADPH), and then protects the structural integrity of tight junctions in cerebral microvascular endothelial cells (Wang et al., 2017a)