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3, in contrast to the Acox1 / cells, LPS treatment induced oxidative stress with the significant intracellular ROS production in the Wt cells, exhibiting approximately 20% increase in LPS-treated cells compared to the untreated control (Fig

The DNA-binding study using agarose gel electrophoresis showed that these complexes interacted with genomic DNA

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Accordingly, preclinical data correlate the environmental disruption of the biological clock, due to shift work and light exposure at night, with hormone-dependent cancers, such as breast and prostate cancer 100,101,102