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Nevertheless, it should not be underestimated that some strains can produce bitter peptides that negatively affect the taste of the fermented product

Brain Pathol 3(4):405412 Friedman LK, Pellegrini-Giampietro DE, Sperber EF et al (1994) Kainate-induced status epilepticus alters glutamate and GABAA receptor gene expression in adult rat hippocampus: an in situ hybridization study [J]

doi: 10.3389/fphys.2015.00397 Received 22 October 2015 Accepted 04 December 2015 Published 23 December 2015 Volume 6 - 2015 Edited by Narasaiah Kolliputi, University of South Florida, USA Reviewed by Lei Liu, University of Florida, USA

Another randomized controlled trial showed that adding Bevacizumab to fluorouracil and leucovorin improved PFS in patients with mCRC for whom first-line irinotecan was judged inappropriate due to their poor functional status [81]