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Carotenoids, such as -carotene, astaxanthin, lutein, and zeaxanthin, are potent antioxidants that can neutralize free radicals and protect cells from oxidative damage (see Table 1) [13, 20, 23]

Bacteria dying off and releasing toxins can cause the body to have an inflammatory response

naringenin 7- O -methyltransferase PAL: Phenylalanine ammonia lyase PCL: Poly-(-caprolactone) PIM-1: Proto-oncogene serine/threonine-protein kinase encoded by the pim-1 gene PKC: Protein kinase C PLA: Poly-dl-lactide PLGA-PEG-COOH: Poly(dl-lactic- co -glycolic acid)- block -poly(ethyleneglycol) carboxylic acid SEM: Scanning electron microscopy SOD: Superoxide dismutase SPE: Solid-phase extraction SWE: Subcritical water extraction TAL: Tyrosine ammonia lyase TBARS: Thiobarbituric acid reactive substances TEAC: Trolox equivalent antioxidant capacity TEM: Transmission electron microscopy TGA-DTG: Thermogravimetric analysis-differential thermogravimetry TLC: Thin layer chromatography UAE: Ultrasound-assisted extraction UDP-Glc: Uridine diphosphate glucose UFGT: Uridine diphosphate glucose flavonoid 3- O -glucosyltransferase UHPLC-PDA(DAD)-ESI/QTOF-MS/MS 2/n : Ultrahigh pressure liquid chromatography coupled with photodiode array detector and electrospray ionization/quadrupole time of flight-mass spectrometry/tandem mass spectrometry detector UV-Vis: Ultraviolet-visible spectrophotometry XPS: X-ray photoelectron spectroscopy XRD: X-ray diffractometry -KG: -ketoglutarate References Aherne SA, OBrien NM

Climacteric 23 , 532538 (2020)