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Post-translational modifications (PTMs) constitute an efficient mechanism for altering the activity, stability, and subcellular location of structural proteins, transcription regulators, and enzymes within cells to regulate ferroptosis 55

These formulation exhibits a encapsulation efficiency ranging from 79.65 3.84%,These complexes had a size between 300 and 500 nm, particle size of 18.74 9.748 nm, a polydispersity index (PDI) of 0.198 0.01, Permeation data indicate that after 24 h, methotrexate was released from the nano-emulsion at 76.83 4.98 g/cm 2 with a flux rate of 2.385 0.61 g/cm 2 /h [160]

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