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Vet J (2008) 176(1):706

Finally, we demonstrate the detection of stress-induced, intracellular interactome changes (actinomycin D treatment) with an in situ variant of the approach, which uses a recombinant biotin ligase and does not require genetic manipulation of the target cell

All experimental procedures were reviewed and approved by the Ethical Committee for the Research of Life Science, Kurume University, and were in compliance with the Animal Research: Reporting in Vivo Experiments guidelines

It may be more relevant in situations that alter homeostasis (e.g., transport disorders, dialysis, malabsorption) or with very low intakes