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53 Ornithine transcarbamylase (OTC) deficiency, a rare Xlinked genetic disorder resulting in accumulation of ammonia, may result in similar clinical findings like lethargy and vomiting, though biochemical findings should display high concentrations of ammonia typical of urea cycle disorders

In addition, exogenous supplemental betaine and endogenous increase in lysine and glutamine could improve lipid metabolism and thus might be regarded as potential treatments of GHD (18, 49)

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Our team with clinical studies on Alzheimers patients has shown that iron deposition in the hippocampus along with decrease in the levels of the antioxidant glutathione in the same area of the brain is one of the important factors of the disease, says Dr Pravat Mandal, senior scientist and former director-in-charge of the National Brain Research Centre The recent approval of three drugs to prevent cognitive decline in Alzheimers patients came as a ray of hope for many but could there be other factors at play