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International journal of molecular sciences , 12 (8), 52135237

Patients with ALF due to WD are appropriately afforded the highest category of priority for liver transplantation by the United Network for Organ Sharing, status 1A, and by Eurotransplant despite the recognition of the underlying chronic liver injury with advanced fibrosis in these patients

Overall, these observations show that mutations in these genes affect mitochondrial function and integrity and, are associated with increases in oxidative stress (Zuo and Motherwell, 2013)

The relationship between body weight and optimal dosing has not been established through controlled trials