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However, the intervention period in the present study was relatively short

Kidney Blood Press Res Nobiletin from Xiaoyu Xiezhuo Decoction: Restoring Mitochondrial Dynamics and Alleviating Renal Ischemia-Reperfusion Injury via M1 Macrophage Modulation

The injury of renal tubular epithelial cells (RTECs) and epithelial-mesenchymal transition (EMT) are the main causes of renal function decline in DKD patients

This phenomenon leads to increased expression of intracellular inflammatory factors, such as IL-6, IL-1, and TNF-, resulting in endocytosis and degradation of FPN1 regulated by hepcidin (Qian et al