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We observed that despite the important role of MyD88 to activate the innate and adaptive immune cells in response to BCG, there was no difference between WT and MyD88 -/- splenocytes derived from animals treated or not with BCG to kill B16-F10 target cells in 1:10 or 1:20 ratio ( Figures 6B, C )

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Under standard conditions, cells were grown in serum-free agar-coated 12-well plates under treatment with 150 nM of BiNPs, Bi@Chi, Bi@Chi-SCR, and Bi@Chi-DEC nanostructures or DMEM medium as controls in nonadherent agar