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This variability comes from genetic polymorphisms and differences in activity of key metabolizing enzymes (eg CYP2E1, NQO1 and myeloperoxidase), co-exposures and other host factors

The scope includes bioactive compounds achievable through realistic dietary intake and purified phytochemicals or concentrated plant extracts-including those derived from traditional Chinese medicine (TCM)

The researchers found that children with autism cannot effectively metabolize certain compounds including acetaminophen, which exacerbates their autistic behaviour

In a series of papers [3436], Ookhtens and colleagues showed that the half-life of glutathione in the liver was quite low, approximately 23 hours, consistent with the result of Lauterburg [47]