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The SAM also participates in the synthesis of phosphatidylcholine, the major phospholipid found in mammalian cells (Vance and Tasseva, 2013)

It is found in every cell of the body, primarily in the liver, where it plays a crucial role in detoxification

Most common adverse reactions included diarrhea, decreased appetite, emesis, lethargy, weight loss and neutropenia

Chew NWS, Mehta A, Goh RSJ, Zhang A, Chen Y, Chong B, Chew HSJ, Shabbir A, Brown A, Dimitriadis GK, Huang DQ, Foo R, Le Roux CW, Figtree GA, Fudim M, Pandey A, Mamas MA, Hausenloy DJ, Mark Richards A, Nicholls SJ, Chan MY, Muthiah MD, Sanyal A, Sperling LS (2025) Cardiovascular-liver-metabolic health: recommendations in screening, diagnosis, and management of metabolic dysfunction-associated steatotic liver disease in cardiovascular disease via modified Delphi approach