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Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y

Liver (hepatic) and kidney safety considerations are equally important, since some supplements that undergo hepatic metabolism or renal excretion can accumulate or interact with chemotherapeutic drugs leading to hepatotoxicity (e.g., kava, high-dose green tea extract) or nephrotoxicity in patients who already suffer from impaired organ function or taking chemotherapy agents known to be nephrotoxic such as cisplatin (208, 209)

Pregnant or nursing mothers, children under the age of 18, or individuals with a known medical condition should consult a physician before using this or any dietary supplement

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