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Liu also hypothesizes that one explanation for the high levels of efficacy is that the vaccines might be triggering a nonspecific inflammatory response to the mRNA that could be heightening its specific immune response, given that the modified nucleoside technique reduced inflammation but hasnt eliminated it completely

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Furthermore, PET imaging in a disseminated mouse model demonstrated tumor cell localization in femur, tibia and spine, highlighting the potential of this antibody-based PET radiopharmaceutical for non-invasive CD38-positive myeloma imaging [101]