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Resilience is determined by the robustness of individual pathways, the efficiency of stress sensing and signaling coordination, and the ability of parallel systems to compensate when one mechanism becomes overwhelmed

Therefore, the focus of the present study is to determine whether 4-OXO-DHA can be identified as a metabolite of DHA in vivo, to examine its effects on critical molecular targets of mammary carcinogenesis in breast cancer cell lines in vitro and to elucidate the structural basis that can account for its inhibition of NF-B

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