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Other potential factors impacting T4 to T3 conversion include: Aging Alcohol [7] Chemotherapy [8] Cigarettes [9] Deiodinase gene variation Diabetes [10] Fasting and calorie restriction [11] Growth hormone deficiency [12] Heavy metals [13] Iodine excess [14] Kidney and liver disease [15] Low progesterone [16] Medications Obesity [17] Pesticides [18] Radiation [19] Soy [20] Surgery [21] Furthermore, in recent years, pharmacogenomics (the study of how a persons genes impact their response to medications) has helped us determine which patients may best benefit from particular medications due to their unique genes

Diffusion tensor imaging study also showed that compared with the healthy, the fractional anisotropy values of white matter fibers in the frontal and temporal areas of post-chemotherapy breast cancer patients were significantly decreased, which were significantly associated with attention and processing/psychomotor speed (Deprez et al., 2011)

This separation protocol was first described for the isolation of DC from mouse Peyers patches, lymph nodes and spleen and for the isolation of Langerhans cells from skin [10-12]