chac1 glutathione Frontiers Human CHAC1 Protein Degrades Glutathione,
Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect journal club Kidney International CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia PLOS One Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv
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