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The gut microbiota in human energy homeostasis and obesity

Its deficiency results in reduced NAD + synthesis and accumulation of its substrate, NAM, leading to increased NNMT activity and further decline in NAD + levels

Supplements may be beneficial for women who: Eat a vegetarian or vegan diet Have confirmed vitamin B12 deficiency Are pregnant (as advised by a doctor) Have absorption disorders Have undergone bariatric surgery Take medications that reduce vitamin B12 absorption Supplements are available as: Tablets Capsules Sublingual tablets Oral sprays Injections (for severe deficiency) Always consult a healthcare professional before starting supplementation

[1] [4] These areas are preferred due to their accessible fatty tissue and ease of self-administration