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Folic acid is also crucial for red blood cell production, and a deficiency of either vitamin can inhibit the proper formation of RBCs, leading to anemia

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ADP insensitivity, assessed by titrating ADP into samples and measuring mitochondrial responses, is when a given concentration of ADP stimulates a smaller change in mitochondrial metabolism

Neither the disulfide lipoic acid (LA) nor GSSSG worked in this manner, and thus served as reliable controls in the high-dose experiments (Figure 1e bars 47 and Figure 2c,d)