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More specifically, the researchers posited that the peptide may have enhanced the expression of Ki-67 and CD98hc that are less intensively synthesized during cell aging. Epithalon also seemed to inhibit the activity of Caspase-3, a crucial enzyme believed to facilitate apoptosis (programmed cell death)

CHOP, C/EBP homologous protein

Int J Mol Sci 23:5500 Yin H, Fu X, Gao H, Gao H, Ma Y, Chen X, Zhang X, Du S-S, Qi Y-K (2022) Hybrid peptide NTP-217 triggers ROS-mediated rapid necrosis in liver cancer cells by induction of mitochondrial leakage