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doi: 10.1093/gerona/gls072

The fat loss effect is gradual but cumulative, with most men reporting the most dramatic changes between weeks 8 and 16 of consistent use

Mesterolone is used not only to increase androgen levels in athletes as an AAS but also for its supposed intrinsic aromatase enzyme antagonist properties as an anti-estrogen ( Medicines used in PTC may cause serious side effects, including blood clots, stroke, and endometrial cancer in women taking SERMs ( Owing to restrictions on the purchase of AAS and PCT products, an international black market for such preparations has developed

For off-label use, insurance coverage is typically not guaranteed, and treatment is usually self-pay