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(2021) demonstrated excellent in vivo regeneration when synovial mesenchymal stem cells (MSCs) were delivered via hybrid chitosanpolycaprolactone (PCL) scaffolds [134, 135]

Hence, more research is required to confirm the precise changes in Parkin and PINK1 levels

In contrast, -LA improved hyperinsulinemia and the higher levels of free fatty acids of the T2DM rats [129], increases antioxidant defense through Nrf2, and reduces inflammation in T2DM (decreases TNF- and Inhibit the expression of NLRP3 and downstream inflammatory factors IL-18 and IL-1) to prevent liver steatosis and relieve HFD-induced liver lipid accumulation in T2DM rats (Table 7)

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