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10.4236/as.2014.513133 94 HusseinN

[1] The majority of eicosanoids require arachidonic acid, which is cleaved from cell membranes by phospholipase A2 (PLA2) enzymes

Children under 75 pounds half the adult dosage

In the hypoxic TME, stabilization of HIF-1 not only enhances glycolytic flux through the upregulation of HK2 and PDPK1, but also supports tumor cell motility and invasiveness (77)