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We included preclinical ( in vitro , in vivo ) and human clinical studies on ASD that reported either redox biomarkers and/or clinical outcomes

Although, most literature on detoxification refers to liver enzymes, as the liver is the site of the majority of detoxification activity for both endogenous and exogenous compounds, however, the first contact the body with the majority of xenobiotics take places in the gastrointestinal tract

In summary, mitochondria can regulate oxidative stress, inflammation, and aging, and drugs targeting mitochondria can be involved in related diseases

Potential treatments for long COVID symptoms Are you experiencing post-COVID headaches or chest pain