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All real-time PCRs were performed three times and all changes in gene expression were reported as multiples of increases relative to the control while GAPDH was used as an internal control and relative gene expression between the experimental groups were determined using MxPro software

A recent study demonstrated that, under heat stress, HSC70 robustly directs GPX4 to CMA, thereby promoting ferroptosis through a marked reduction in GPX4 levels in liver cells (Wang T

TB-500 has been associated with improved collagen alignment and mechanical strength in ligament repair models.- BPC-157 enhanced fibroblast survival, migration, and organization under stress conditions, possibly through FAK-paxillin activation.- Both peptides appear to influence tendon outgrowth and connective tissue regeneration

Comprehensive reviews describe BPC-157 within the broader framework of cytoprotection in the gastrointestinal tract and beyond (Sikiric 2019, review)