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Intriguingly, the top three biomarkers including proline, L-kynurenine, and taurine have been reported to be associated with certain cancers including lung cancer, breast cancer, and gastric cancer 14,15,16,17

However, development of CAR-T cells or vaccine therapy as senolityc treatment remain, for the moment, difficult because the permanent activation of these therapies could lead to several side effects and potentially eradicate positive activity of senescence

Arch Toxicol 89:22732289

CSPI has argued that move would threaten the publics health because the FDA doesn't review supplements for safety or effectiveness before they hit the market