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Research is still emerging, but medically supervised use with regular monitoring appears favorable

By lowering how much you eat and supporting your metabolism, this combined action can produce substantial weight loss up to 22.5% of body weight on the 15 mg dose in the SURMOUNT-1 trial

Based on this basis, my team and I further developed a high-fidelity Cas13Y (hfCas13Y) with efficient editing and very low off-target activities, which was also published in Nature Biotechnology 2022, laying out the technical foundation of the CRISPR/Cas13 system for future clinical applications. About BRIGHT Trial (NCT06623279) This open-label, multicenter, Phase 1, dosing finding trial (an open-la B el, dose-escalation study for CRISPR/Cas13- R NA target I n G t H erapy for the T reatment of neovascular age-related macular degeneration, BRIGHT ) is designed to evaluate the safety and tolerability of high-fidelity CRISPR-Cas13 RNA-editing therapy targeting knock-down of VEGF-A mRNA (HG202) in patients with nAMD, affecting nearly 190 million people over the age of 60 worldwide

Glutathione combats oxidative stress by neutralizing free radicals, thereby reducing the risk of cellular damage and inflammation