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Your Overall Health Underlying health conditions, such as gastrointestinal disorders (like Crohns disease, celiac disease, or atrophic gastritis) that impair nutrient absorption, or certain medications you may be taking, can influence how your body absorbs and utilizes B12

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However, like MMA, false positive results may occur if one has kidney issues

So, while you absorb over 50 per cent of a one microgram dose, you might only absorb 16 per cent of 10 micrograms, three per cent of 50 micrograms, two per cent of 500 micrograms and just 1.3 per cent of 1,000 micrograms