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A systematic review of modern specialized literature and relevant scientific data was carried out

Ferroptosis: past, present and future

The glutathione system and melanogenesis Glutathione and melanogenesis It has been shown that GSH not only acts as an antioxidant by scavenging free radicals but is also involved in pheomelanin formation (Figure 2)

Yet, overproduction of reactive oxygen species (ROS), induced by environmental toxins, inflammation, or mitochondrial dysfunction, overwhelms the cellular antioxidant defense system, resulting in oxidative stress [27]