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Research Applications MT-2 has been utilized as a molecular probe in controlled experimental systems examining: Melanocortin receptor pharmacology and subtype selectivity (MC1RMC5R) Melanogenesis and pigmentation signaling cascades Hypothalamic energy homeostasis and appetite regulation models Central melanocortin circuit characterization Cutaneous photoprotection and UV-induced DNA damage models Peripheral metabolic and adipogenic signaling Autonomic nervous system modulation research

By activating MC4R, PT-141 stimulates pathways involved in sexual arousal and desire, leading to an increase in libido for both men and women (2)

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