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No peer-reviewed primary human comparison was identified in the sources reviewed for this guide

higher doses use more

Moreover, up to 24.2% of CD patients may require second surgery within the 5 years of the primary surgery (Frolkis et al., 2014)

For instance, prolotherapy might reduce a patients daily pain from a 7/10 to a 3/10 and cut down subluxations significantly, a great result, but it wont remove the EDS or make the persons joints normal. Recognizing these treatments as part of a chronic management strategy will lead to greater satisfaction and less frustration