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to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies

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No improvement with home care : If youve tried self-care measures and over-the-counter products without significant improvement

Between 50 and 200 per 100 000 people in the UK and 150 per 100 000 people in the US are affected.2 It can affect all age groups, but is seen more commonly in adults over 70 years old.1 Because of its association with autoimmune disorders such as autoimmune thyroiditis, Addisons disease, vitiligo, and type 1 diabetes, a personal or family history of these conditions increases the likelihood of pernicious anaemia.34 Log in Log in using your username and password Log in through your institution Subscribe from 184 * Subscribe and get access to all BMJ articles, and much more