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Some of the key applications of GSH in LAB and their proposed mechanisms are discussed here

Celastrol inhibits oligodendrocyte and neuron ferroptosis to promote spinal cord injury recovery

The reaction is initiated via the attack of a hydroxide ion at the C5 ester

Additionally, activation of the Panx1 gene triggers the CAN-DRP1 signaling pathway, inducing mitochondrial dynamic imbalance, disrupting tight junctions, and promoting apoptosis, all of which contribute to ALI (Xu, 2023)