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To this end, we used small molecules that reduce PrP expression by different mechanisms

however, it is highly recommended to conduct a patch test prior to regular application of skincare products

Reported side effects Mild headache or fatigue typically transient during initial use Mild gastrointestinal discomfort reported in some oral formulation users Sleep disruption or irritability potential sign of overstimulation Theoretical safety concerns Critical note: Because Dihexa activates the HGF/c-Met pathway which promotes cellular growth and repair there is a theoretical concern that it could potentially stimulate unwanted cell proliferation in individuals with active cancer or high cancer risk

1.4 P62-dependent Nrf2 Regulation Additional pieces of evidence suggest that other regulators also may activate the Nrf2 pathway