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Oxidative stress can lead to chronic inflammation, which in turn, can cause collagen fragmentation and disorganization of collagen fibers and skin cell functions, and thus contribute to skin diseases

In fact, overproduction of ROS may lead to a decrease in respiratory enzyme activities and mitochondrial membrane potential (MMP) 11,12,13

doi: 10.3389/fnmol.2021.742294 Received 16 July 2021 Accepted 23 August 2021 Published 09 September 2021 Volume 14 - 2021 Edited by Jun Hirayama, Komatsu University, Japan Reviewed by Sooyoung Chung, Ewha Womans University, South Korea

All GSSCys assays were started by the addition of GSSCys